重组小鼠Ppbp蛋白

小鼠

大肠杆菌

Lys 40 - Tyr 113

A DNA sequence encoding the mouse Ppbp (Q9EQI5) (Lys40-Tyr113) was expressed with a polyhistidine tag at the N-terminus.

> 80 % as determined by SDS-PAGE.

The recombinant mouse Ppbp consists 92 amino acids and predicts a molecular mass of 10.4 kDa.

TGB1; LA-PF4; SCYB7; TGB; TC2; LDGF; NAP-2; PLATELET BASIC PROTEIN; CTAP-III; CXCL7; PBP; CHEMOKINE (C-X-C MOTIF) LIGAND 7; NAP-2-L1; THBGB1; RATTUS NORVEGICUS; MDGF; CTAP3; THBGB; B-TG1; 2400003M24RIK; CTAPIII; AI854500; NEUTROPHIL ACTIVATING PEPTIDE-2; BETA-TG; TC1

Chemokine (C-X-C motif) ligand 7, isoform CRA_b

Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2 / PPBP / CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils.

Lyophilized from sterile 1/1000 TFA, 15 % acetonitrile.
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

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Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.