- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:ELISA, WB, IHC
- 特异性:Human; other species not tested.
产品详情
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产品名称
MSH2 antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG1
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抗体描述
MSH2 Mouse Monoclonal antibody. Positive WB detected in Colo320 cells, A2780 cells, HeLa cells. Positive IHC detected in human colon cancer tissue. Observed molecular weight by Western-blot: 100-105 kDa
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抗体应用
ELISA, WB, IHC
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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特异性
Human; other species not tested.
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蛋白别名
COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MSH2, MutS protein homolog 2
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制备方法
This antibody was obtained by immunization of MSH2 recombinant protein (Accession Number: NM_000251). Purification method: Caprylic acid/ammonium sulfate precipitation.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
MSH2, named for its homologous to the E.coli MutS gene, takes part in DNA mismatch repair(MMR) to maintain the stability of DNA. MSH2 contains a helix-turn-helix domain, which responds for binding to DNA. Also, MSH2 has a direct role in mutation avoidance and micro-satellite stability in cell.