重组人PCSK1蛋白

人

人胚胎肾细胞（HEK293）

Met 1 - Arg 617

A DNA sequence encoding the human PCSK1 (NP_000430.3) (Met 1-Arg 617) was fused with a polyhistidine tag at the C-terminus.

> 95 % as determined by SDS-PAGE

The purified recombinant human PCSK1 consists of 518 amino acids after removal of the pro peptide due to autocatalytic processing, corresponding to the active form (aa 111-617), and has a predicted molecular mass of 57.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the active rh PCSK1 is approximately 66 kDa due to glycosylation.

MGC124320; MGC124321; PHPP-1; NEUROENDOCRINE CONVERTASE 1; PROHORMONE CONVERTASE 1; PROPEPTIDE-PROCESSING PROTEASE; NEC1; NEC 1; PROHORMONE CONVERTASE 3; PROPROTEIN CONVERTASE 1; NEC-1; PCSK1; BMIQ12; SPC3; PROHORMONE CONVERTASE 1/3; PC3; PC1

Neuroendocrine convertase 1

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.

Lyophilized from sterile 25mM Tris, 150mM NaCl, pH 7.5
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

< 1.0 EU per μg of the protein as determined by the LAL method

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.