- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP, IF
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
-
产品名称
NFIL3 antibody
-
抗体类型
多克隆
-
抗体来源
兔
-
抗体亚型
兔IgG
-
抗体描述
NFIL3 Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells, HEK-293 cells, HeLa cells, human testis tissue, K-562 cells, mouse heart tissue, mouse lung tissue. Positive IP detected in HeLa cells. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 63 kDa,50-51 kDa
-
抗体应用
ELISA, WB, IP, IF
-
应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:500-1:5000
IF: 1:50-1:500
-
特异性
Human,Mouse,Rat; other species not tested.
-
蛋白别名
E4 promoter binding protein 4, E4BP4, IL3BP1, NF IL3A, NFIL3, NFIL3A
-
制备方法
This antibody was obtained by immunization of NFIL3 recombinant protein (Accession Number: XM_047423422). Purification method: Antigen affinity purified.
-
组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
储存方法
Store at -20℃. DO NOT ALIQUOT
-
背景介绍
NFIL3, also named as E4BP4 and IL3BP1, belongs to the bZIP family and NFIL3 subfamily. It represses transcription from promoters with activating transcription factor (ATF) sites. NFIL3 activates transcription from the interleukin-3 promoter in T-cells. It competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). It is a component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. NFIL3 protects pro-B cells from programmed cell death. It is a key regulator of TH2 responses(PMID:21499227).