NKRF antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, WB, IP
  • 特异性:Human,Mouse,Rat; other species not tested.

产品详情

  • 产品名称
    NKRF antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    NKRF Rabbit Polyclonal antibody. Positive IP detected in A549 cells. Positive WB detected in Jurkat cells, A431 cells, A549 cells, HepG2 cells, PC-3 cells. Observed molecular weight by Western-blot: 100 kDa
  • 抗体应用
    ELISA, WB, IP
  • 应用推荐

    Recommended Dilution:

    WB: 1:1000-1:10000

    IP: 1:500-1:5000

  • 特异性
    Human,Mouse,Rat; other species not tested.
  • 蛋白别名
    ITBA4, NF kappa B repressing factor, NKRF, NRF, Protein ITBA4, Transcription factor NRF
  • 制备方法
    This antibody was obtained by immunization of NKRF recombinant protein (Accession Number: NM_001173488). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    NKRF, also named as Protein ITBA4 or Transcription factor NRF, is a 690 amino acid protein, which contains one G-patch domain and one R3H domain. NKRF is Widely and constitutively expressed, with lower level in colon, peripheral blood lymphocytes, lung and kidney. NKRF interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. NKRF is involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity.
  • 参考文献
    • Huang L, Liu Y, Wang L. Down-regulation of miR-301a suppresses pro-inflammatory cytokines in Toll-like receptor-triggered macrophages. Immunology. 140(3):314-22. 2013.
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!