NOS2 Polyclonal Antibody

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  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:IF
  • 特异性:Human

产品详情

  • 产品名称
    NOS2 Polyclonal Antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Polyclonal antibody to NOS2
  • 抗体应用
    IF
  • 应用推荐
    IF 1:50 - 1:200
  • 特异性
    Human
  • 蛋白别名
    NOS2, HEP-NOS, INOS, NOS, NOS2A, nitric oxide synthase 2
  • 制备方法
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 500-730 of human NOS2 (NP_000616.3).
  • 组分
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 储存方法
    Store at -20℃. Avoid freeze / thaw cycles.
  • 背景介绍
    Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.
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