重组人S100A6蛋白

人

大肠杆菌

Met 1 - Gly 90

A DNA sequence encoding the human S100A6 (NP_055439.1) (Met 1-Gly 90) was expressed.

> 95 % as determined by SDS-PAGE

The recombinant human S100A6 consisting of 90 amino acids and migrates with an apparent molecular mass of 20 & 10 kDa corresponding to dimeric and monomeric form as estimated in SDS-PAGE under Non-reduced condition.

CALCYCLIN; 2A9; CACY; S100A6; 5B10; PRA; CABP

Protein S100-A6

S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins, and functions in prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.

Lyophilized from sterile PBS, pH 7.4
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

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Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.