PSEN2-Specific antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, IHC
  • 特异性:Human, Mouse; other species not tested.

产品详情

  • 产品名称
    PSEN2-Specific antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    PSEN2-Specific Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human breast cancer tissue, human colon tissue, human placenta tissue.
  • 抗体应用
    ELISA, IHC
  • 应用推荐

    Recommended Dilution:

    IHC: 1:20-1:200

  • 特异性
    Human, Mouse; other species not tested.
  • 蛋白别名
    AD3L, AD3LP, AD4, AD5, E5 1, Presenilin 2, PS 2, PS2, PSEN2, PSNL2, STM 2, STM2
  • 制备方法
    This antibody was obtained by immunization of Peptide (Accession Number: NM_000447). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    Presenilins can regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. These transmembrane proteins are considered to be involved in early onset of Alzheimer's disease. Presenilin 2 mainly localizes in large neurons. It exists in a heterodimeric complex formed from the endoproteolytically processed amino-terminal (34 kDa) and carboxy-terminal (about 23 kDa) fragments.This antibody is specific to presenilin 2. It will not bind presenilin 1.

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