- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
QKI antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
QKI Rabbit Polyclonal antibody. Positive WB detected in K-562 cells. Positive IP detected in K-562 cells. Observed molecular weight by Western-blot: 38kd
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抗体应用
ELISA, WB, IP
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:1000
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
DKFZp586I0923, HKQ, Hqk, HqkI, Protein quaking, QK1, QK3, QKI
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制备方法
This antibody was obtained by immunization of QKI recombinant protein (Accession Number: NM_006775). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
QKI belongs to a family of RNA-binding proteins, which have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. It involves in regulation of RNA splicing, export of target RNAs from the nucleus, translation of proteins, and RNA stability. Also it required to protect and promote stability of mRNAs such as MBP and CDKN1B. Beside, it acts as a regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia.