- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
RASGRP2 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
RASGRP2 Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue, mouse liver tissue, mouse lung tissue. Observed molecular weight by Western-blot: 48kd
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抗体应用
ELISA, WB
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
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特异性
Human, Mouse; other species not tested.
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蛋白别名
CALDAG GEFI, Cdc25 like protein, CDC25L, F25B3.3 kinase like protein, hCDC25L, MCG7, RAS guanyl releasing protein 2, RASGRP2
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制备方法
This antibody was obtained by immunization of Peptide (Accession Number: NM_153819). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
RASGRP2, also named as CDC25L and MCG7, belongs to the RASGRP family. It functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. RASGRP2 may also activate other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. RASGRO2 functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. It may function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway. The antibody recognizes the C-term of RASGRP2.