RCC1 Polyclonal Antibody

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  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:WB, IHC, IF
  • 特异性:Human, Mouse, Rat

产品详情

  • 产品名称
    RCC1 Polyclonal Antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Polyclonal antibody to RCC1
  • 抗体应用
    WB, IHC, IF
  • 应用推荐
    WB 1:1000 - 1:2000
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
  • 特异性
    Human, Mouse, Rat
  • 蛋白别名
    RCC1, CHC1, RCC1-I, SNHG3-RCC1, regulator of chromosome condensation
  • 制备方法
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RCC1 (NP_001260.1).
  • 组分
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 储存方法
    Store at -20℃. Avoid freeze / thaw cycles.
  • 背景介绍
    Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA.
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