- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IF, IP
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
RtcB-Specific antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
RtcB-Specific Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive WB detected in HeLa cells, HepG2 cells, mouse brain tissue. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 55kd
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抗体应用
ELISA, WB, IF, IP
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应用推荐
Recommended Dilution:
WB: 1:1000-1:10000
IP: 1:200-1:2000
IF: 1:10-1:100
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特异性
Human, Mouse; other species not tested.
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蛋白别名
C22orf28, FAAP, HSPC117, RtcB
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制备方法
This antibody was obtained by immunization of RtcB-Specific recombinant protein (Accession Number: NM_014306). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
RTCB (also known as HSPC117, C22orf28, FAAP and D10Wsu52e) is an essential subunit of a tRNA ligase complex that is involved in RNA repair and stress-induced splicing. As a multifunctional protein, RTCB is also a cell adhesion protein and is important in embryo and placenta development. Recently RTCB has been identified as UPR RNA ligase catalyzing unconventional XBP1 mRNA splicing. This antibody specifically recognizes endogenous RTCB protein. (25087875)
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参考文献
- Lu Y, Liang FX, Wang X. A synthetic biology approach identifies the mammalian UPR RNA ligase RtcB. Molecular cell. 55(5):758-70. 2014.