- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:ELISA, WB
- 特异性:Human; other species not tested.
产品详情
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产品名称
SALL4 antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG1
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抗体描述
SALL4 Mouse Monoclonal antibody. Positive WB detected in K-562 cells. Observed molecular weight by Western-blot: 165 kDa
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抗体应用
ELISA, WB
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
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特异性
Human; other species not tested.
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蛋白别名
dJ1112F19.1, DRRS, HSAL4, sal like 4 (Drosophila), Sal like protein 4, SALL4, Zinc finger protein SALL4, ZNF797
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制备方法
This antibody was obtained by immunization of SALL4 recombinant protein (Accession Number: NM_020436). Purification method: Protein G purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
SALL4, also named as Sal-like protein 4 or Zinc finger protein 797, Contains 7 C2H2-type zinc fingers and belongs to the sal C2H2-type zinc-finger protein family. SALL4 is constitutively expressed in acute myeloid leukemia. The constitutive expression of SALL4in mice is sufficient to induce MDS-like symptoms and transformation to AML that is transplantable. SALL4 is able to bind beta-catenin and activate the Wnt/beta-catenin signaling pathway. Sequence analysis of the larger cDNA fragment isolated revealed a single, large open-reading frame, designated as SALL4A, that started from a strong consensus initiation sequence and was expected to encode 1053 amino acids. The other splicing variant of SALL4, designated SALL4B, lacked the region corresponding to amino acids 385 to 820 of the full-length SALL4A. The putative protein encoded by SALL4B cDNA was expected to consist of 617 amino acids.