- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IF, IP
- 特异性:Human; other species not tested.
产品详情
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产品名称
SART1 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
SART1 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, Jurkat cells. Positive IP detected in mouse brain tissue. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 110 kDa
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抗体应用
ELISA, WB, IF, IP
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IF: 1:20-1:200
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特异性
Human; other species not tested.
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蛋白别名
Ara1, Hom s 1, HOMS1, hSART 1, hSnu66, SART 1, SART1, SART1259, SNRNP110, Snu66, SNU66 homolog
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制备方法
This antibody was obtained by immunization of SART1 recombinant protein (Accession Number: NM_005146). Purification method: Antigen Affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Squamous cell carcinoma antigen recognized by T cells (SART1), also known as U4/U6.U5 tri-snRNP-associated 110 kDa protein, is a ubiquitously expressed protein that is involved in mRNA splicing and the regulation of cell proliferation. It has been identified as regulator of c-FLIP and drug-induced activation of caspase 8. The SART1 gene encodes two proteins, the SART1(800) protein is located in the nucleus of the majority of proliferating cells, while the SART1(259) protein is located in the cytosol of epithelial cancers. Genetic variation in the SART1 gene may be associated with breast cancer development. This antibody recognizes the endogenous 800-amino acid SART1, which migrates with an apparent molecular mass of 110 kDa in SDS-PAGE. (PMID: 22027693; 9449708; 19377877; 11350945)