- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP, IHC
- 特异性:Human; other species not tested.
产品详情
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产品名称
SFRP4 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
SFRP4 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells. Positive IP detected in HeLa cells. Positive IHC detected in human cervical cancer tissue, human breast cancer tissue. Observed molecular weight by Western-blot: 41-51 kDa; 55 kDa
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抗体应用
ELISA, WB, IP, IHC
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:50-1:500
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特异性
Human; other species not tested.
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蛋白别名
FRP 4, FRPHE, sFRP 4, SFRP4
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制备方法
This antibody was obtained by immunization of SFRP4 recombinant protein (Accession Number: NM_003014). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRP4 functions as a suppressor of tumor growth via inhibition of the Wnt signaling pathway.Downregulation or deletion of SFRP4 has been reported in several cancers and cell lines such as endometrial cancer, ovarian cancer, lung cancer,and others. This antibody got 41-51 kDa and 55 kDa bands in western blotting maybe due to differential posttranslational protein modification.
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参考文献
- Mortensen MM, Høyer S, Lynnerup AS. Expression profiling of prostate cancer tissue delineates genes associated with recurrence after prostatectomy. Scientific reports. 5:16018. 2015.