- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
-
产品名称
SFRS5 antibody
-
抗体类型
多克隆
-
抗体来源
兔
-
抗体亚型
兔IgG
-
抗体描述
SFRS5 Rabbit Polyclonal antibody. Positive WB detected in A549 cells.
-
抗体应用
ELISA, WB
-
应用推荐
Recommended Dilution:
WB: 1:200-1:1000
-
特异性
Human,Mouse,Rat; other species not tested.
-
蛋白别名
Delayed early protein HRS, HRS, Pre mRNA splicing factor SRP40, SFRS5, SRP40, SRSF5
-
制备方法
This antibody was obtained by immunization of SFRS5 recombinant protein (Accession Number: NM_001039465). Purification method: Antigen affinity purified.
-
组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
储存方法
Store at -20℃. DO NOT ALIQUOT
-
背景介绍
SR proteins own a characteristic C-terminal Ser/Arg-rich repeat (RS domain) of variable length and constitute a family of highly conserved nuclear phosphoproteins that can function as both essential and alternative pre-mRNA splicing factors [PMID:7556075]. The binding of SR proteins to pre-mRNA appears to be one of the earliest steps in spliceosome assembly, enhancing the binding of U1 snRNP to the 5' splice site to form a commitment complex [PMID:1577277 ]. Alternative splicing has a major role in the regulation of gene expression. SFRS5 belongs to the serine/arginine (SR) protein family of regulators of alternative pre-mRNA splicing [PMID:9244433].