- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:ELISA, WB
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
SMN (Human,Mouse,Rat) antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG2b
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抗体描述
SMN (Human,Mouse,Rat) Mouse Monoclonal antibody. Positive WB detected in 293 cells, HepG2 cells, Raji cells. Observed molecular weight by Western-blot: 38 kDa
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抗体应用
ELISA, WB
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
C BCD541, Component of gems 1, FLJ76644, Gemin 1, SMN, SMN1, SMN1, SMN, SMN2, SMNC, SMNT, Survival motor neuron protein
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制备方法
This antibody was obtained by immunization of SMN (Human,Mouse,Rat) recombinant protein (Accession Number: NM_022875). Purification method: Protein A purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
The survival of motor neurons (SMN) genes are the disease genes of spinal muscular atrophy (SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody 60154-2-Ig can recognize human,mouse and rat SMN gene.