- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC, WB
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
smooth muscle actin specific antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
smooth muscle actin specific Rabbit Polyclonal antibody. Positive WB detected in mouse colon tissue, mouse stomach tissue. Positive IHC detected in human heart tissue, human colon cancer tissue, human colon tissue, human hepat℃irrhosis tissue, mouse colon tissue, rat colon tissue. Observed molecular weight by Western-blot: 42 kDa
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抗体应用
ELISA, IHC, WB
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, ACTA2 Smooth muscle Actin Specific, Actin, aortic smooth muscle, Alpha actin 2, Alpha SMA, Alpha SMA Specific, a-SMA, smooth muscle actin, α SMA
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制备方法
This antibody was obtained by immunization of Peptide (Accession Number: NM_001613). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
ACTA2, also named as a-SMA,AAT6;ACTSA belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6). The immunogen of this antibody is a specific domain of ACTA2. This antibody stains the aorta only.
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参考文献
- Shi H, Zhang Y, Fu S, Lu Z, Ye W, Xiao Y. Angiotensin II as a morphogenic cytokine stimulating fibrogenesis of human tenon's capsule fibroblasts. Investigative ophthalmology & visual science. 56(2):855-64. 2015.
- Dan J, Sun X, Li W. 5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Promotes Phenotypic Switching from Dedifferentiated to Differentiated Phenotype via Reactive Oxygen Species and p38 Mitogen-Activated Protein Kinase in Vascular Smooth Muscle Cells. Ultrasound in medicine & biology. 41(6):1681-9. 2015.
- Zhao X, Jiang S, Liu S. Optimization of intrinsic and extrinsic tendon healing through controllable water-soluble mitomycin-C release from electrospun fibers by mediating adhesion-related gene expression. Biomaterials. 61:61-74. 2015.
- Lu L, Wang J, Lu H. MicroRNA-130a and -130b enhance activation of hepatic stellate cells by suppressing PPARγ expression: A rat fibrosis model study. Biochemical and biophysical research communications. 465(3):387-93. 2015.