- 抗体应用:ELISA, IHC, IF, IP, WB, FC
- 特异性:Human,Mouse,Rat; other species not tested.
Spartin, SPG20 antibody
Spartin, SPG20 Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in NIH/3T3 cells, HEK-293 cells, HeLa cells, human brain tissue, mouse brain tissue, rat brain tissue, SH-SY5Y cells. Positive FC detected in HepG2 cells. Positive IHC detected in human gliomas tissue. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 75 kDa,84 kDa
ELISA, IHC, IF, IP, WB, FC
Human,Mouse,Rat; other species not tested.
KIAA0610, SPARTIN, Spastic paraplegia 20 protein, SPG20, TAHCCP1
This antibody was obtained by immunization of Spartin, SPG20 recombinant protein (Accession Number: NM_015087). Purification method: Antigen affinity purified.
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20℃. DO NOT ALIQUOT
SPG20 (spastic paraplegia 20) gene encodes a multifunctional Spartin protein. SPG20 protein is highly expressed in adipose tissue and may be implicated in endosomal trafficking and microtubule dynamics. SPG20 is mutated in Troyer syndrome, a hereditary spastic paraplegia defined by degeneration of upper motor neurons, recent study showed that regulation of SPG20 on mitochondrial calcium homeostasis may contribute to the pathophysiology of Troyer syndrome. Hypermethylation of SPG20 promoter, found in colorectal cancer paitents, may play a role in cytokinesis arrest in colorectal tumorigenesis.