- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC
- 特异性:Human; other species not tested.
产品详情
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产品名称
SPON2 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
SPON2 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue, human prostate hyperplasia tissue.
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抗体应用
ELISA, IHC
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应用推荐
Recommended Dilution:
IHC: 1:20-1:200
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特异性
Human; other species not tested.
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蛋白别名
DIL 1, DIL1, M spondin, Mindin, SPON2, Spondin 2
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制备方法
This antibody was obtained by immunization of SPON2 recombinant protein (Accession Number: NM_001199021). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
SPON2 (Spondin 2), also known as Mindin, is a member of the F-spondin family of secreted extracellular matrix proteins. This protein has been implicated in axon guidance, immune response and adhesion. SPON2 is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (PMID: 14691481). It also functions as an integrin ligand for inflammatory cell recruitment and T-cell priming (PMID: 19153605). Besides, SPON2 has been reported as a prognostic biomarker for ovarian and prostate cancer (PMID: 17490732; 22615945; 23665271).