- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:ELISA, WB
- 特异性:Human, Pig; other species not tested.
产品详情
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产品名称
SRPX2 antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG2b
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抗体描述
SRPX2 Mouse Monoclonal antibody. Positive WB detected in pig lung tissue, A549 cells. Observed molecular weight by Western-blot: 53 kDa
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抗体应用
ELISA, WB
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
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特异性
Human, Pig; other species not tested.
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蛋白别名
BPP, CBPS, PMGX, RESDX, SRPUL, SRPX2
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制备方法
This antibody was obtained by immunization of SRPX2 recombinant protein (Accession Number: NM_014467). Purification method: Protein A purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
SRPX2 (sushi-repeat-containing protein, X-linked 2) is a secreted protein expressed in neurons of the human adult brain, including the rolandic area (PMID: 20874700). Firstly described as sushi-repeat protein up-regulated in leukemia (SPRUL) in leukemia cells with dysregulated expression at the transcriptional level, SRPX2 has been recently shown as a multifunctional protein. SRPX2 is a ligand for uPAR, the urokinase-type plasminogen activator (uPA) receptor (PMID: 18718938). It is involved in seizure disorders, angiogenesis and cellular adhesion (PMID: 22242148; 19667118; 16497722). The involvement of SRPX2 in disorders of language cortex and cognition suggests it has an important role in the perisylvian region critical for language and cognitive development (PMID: 16497722).