- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
-
产品名称
SYNCRIP antibody
-
抗体类型
多克隆
-
抗体来源
兔
-
抗体亚型
兔IgG
-
抗体描述
SYNCRIP Rabbit Polyclonal antibody. Positive WB detected in A431 cells, HEK-293 cells, Jurkat cells. Positive IP detected in A431 cells. Observed molecular weight by Western-blot: 62-74 kDa
-
抗体应用
ELISA, WB, IP
-
应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
-
特异性
Human,Mouse,Rat; other species not tested.
-
蛋白别名
dJ3J17.2, GRY RBP, hnRNP Q, HNRPQ, HNRPQ1, NS1 assOCiated protein 1, NSAP1, pp68, RP1 3J17.2, SYNCRIP
-
制备方法
This antibody was obtained by immunization of SYNCRIP recombinant protein (Accession Number: NM_001159674). Purification method: Antigen affinity purified.
-
组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
储存方法
Store at -20℃. DO NOT ALIQUOT
-
背景介绍
Synaptotagmin-binding, cytoplasmic RNA-interacting protein(SYNCRIP), also identified as hnRNP Q, involves in mRNA processing mechanisms. It's component of the CRD-mediated complex that promotes MYC mRNA stability. Also it is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences.