TADA2A Polyclonal Antibody

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  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:WB
  • 特异性:Human, Mouse, Rat

产品详情

  • 产品名称
    TADA2A Polyclonal Antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Polyclonal antibody to TADA2A
  • 抗体应用
    WB
  • 应用推荐
    WB 1:500 - 1:2000
  • 特异性
    Human, Mouse, Rat
  • 蛋白别名
    TADA2A, ADA2, ADA2A, KL04P, TADA2L, hADA2, transcriptional adaptor 2A
  • 制备方法
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-443 of human TADA2A (NP_001159577.2).
  • 组分
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 储存方法
    Store at -20℃. Avoid freeze / thaw cycles.
  • 背景介绍
    Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.
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