- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
TFIIE beta antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
TFIIE beta Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, A375 cells. Observed molecular weight by Western-blot: 34kd
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抗体应用
ELISA, WB
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
GTF2E2, TF2E2, TFIIE B, TFIIE beta
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制备方法
This antibody was obtained by immunization of TFIIE beta recombinant protein (Accession Number: XM_024447138). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
The general transcription factor IIE (TFIIE) is an essential component of the eukaryotic RNA polymerase II initiation complex, which plays pivotal roles in initiation of protein-coding gene transcription (PMID: 7829083). Transcription initiation factor IIE comprises two subunits, TFIIE-alpha and TFIIE-beta, two chains of which together form a tetramer. TFIIE-beta is encoded by GTF2E2 gene and contains TFIIE beta-DNA binding domain. It mainly functions to recruit TFIIH to the initiation complex and stimulate RNA polymerase II kinase activity (PMID: 10792464).
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参考文献
- De Cegli R, Iacobacci S, Flore G. Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation. Nucleic acids research. 41(2):711-26. 2013.