TFIIE beta antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, WB
  • 特异性:Human,Mouse,Rat; other species not tested.

产品详情

  • 产品名称
    TFIIE beta antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    TFIIE beta Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, A375 cells. Observed molecular weight by Western-blot: 34kd
  • 抗体应用
    ELISA, WB
  • 应用推荐

    Recommended Dilution:

    WB: 1:200-1:2000

  • 特异性
    Human,Mouse,Rat; other species not tested.
  • 蛋白别名
    GTF2E2, TF2E2, TFIIE B, TFIIE beta
  • 制备方法
    This antibody was obtained by immunization of TFIIE beta recombinant protein (Accession Number: XM_024447138). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    The general transcription factor IIE (TFIIE) is an essential component of the eukaryotic RNA polymerase II initiation complex, which plays pivotal roles in initiation of protein-coding gene transcription (PMID: 7829083). Transcription initiation factor IIE comprises two subunits, TFIIE-alpha and TFIIE-beta, two chains of which together form a tetramer. TFIIE-beta is encoded by GTF2E2 gene and contains TFIIE beta-DNA binding domain. It mainly functions to recruit TFIIH to the initiation complex and stimulate RNA polymerase II kinase activity (PMID: 10792464).
  • 参考文献
    • De Cegli R, Iacobacci S, Flore G. Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation. Nucleic acids research. 41(2):711-26. 2013.
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