- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC, IP
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
UPK3B antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
UPK3B Rabbit Polyclonal antibody. Positive IHC detected in human bladder tissue. Positive IP detected in mouse testis tissue. Observed molecular weight by Western-blot: 34 kDa
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抗体应用
ELISA, IHC, IP
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应用推荐
Recommended Dilution:
IP: 1:200-1:1000
IHC: 1:20-1:200
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特异性
Human, Mouse; other species not tested.
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蛋白别名
FLJ32198, P35, UP3b, UPIIIb, UPK3B, uroplakin 3B, Uroplakin IIIb
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制备方法
This antibody was obtained by immunization of UPK3B recombinant protein (Accession Number: BC004304). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-3b (UPK3B), also named as p35, is a single-pass type I membrane protein. This protein dimerizes with uroplakin-1b (UPK1B) to exit out of endoplasmic reticulum, which is is an important early step in urothelial plaque assembly (PMID: 12446744).