USP1 antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, WB, IHC, IP
  • 特异性:Human,Mouse,Rat; other species not tested.

产品详情

  • 产品名称
    USP1 antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    USP1 Rabbit Polyclonal antibody. Positive IP detected in HEK-293 cells. Positive WB detected in HEK-293 cells, HeLa cells. Positive IHC detected in human cervical cancer tissue. Observed molecular weight by Western-blot: 110kd, 100kd
  • 抗体应用
    ELISA, WB, IHC, IP
  • 应用推荐

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:1000

    IHC: 1:20-1:200

  • 特异性
    Human,Mouse,Rat; other species not tested.
  • 蛋白别名
    Deubiquitinating enzyme 1, hUBP, ubiquitin specific peptidase 1, Ubiquitin thiolesterase 1, UBP, USP1
  • 制备方法
    This antibody was obtained by immunization of USP1 recombinant protein (Accession Number: NM_001017416). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    USP1(Ubiquitin carboxyl-terminal hydrolase 1) is a negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2.It is Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA.This protein, which consists of 785 amino acids with a deduced molecular mass of 88.2 kDa, possesses His and Cys domains that are highly conserved in all members of the ubiquitin-specific processing (UBP) family of proteases(PMID:9806842). The USP1 enzyme can undergo autocleavage, resulting in a 100 kDa N-terminal fragment and a 14 kDa C-terminal fragment(PMID:18082604).
  • 参考文献
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