重组人ADA蛋白

人

杆状病毒 - 昆虫细胞

Met 1 - Leu 363

A DNA sequence encoding the human ADA (P00813) (Met1-Leu363) was expressed with a C-terminal polyhistidine tag.

> 95 % as determined by SDS-PAGE

The secreted recombinant human ADA consists of 373 amino acids and predicts a molecular mass of 42.1 KDa. The apparent molecular mass of the protein is approximately 44 KDa in SDS-PAGE under reducing conditions.

RP23-144O20.2; ADENOSINE AMINOHYDROLASE; ADENOSINE DEAMINASE; ADA

Adenosine deaminase

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4.
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

< 1.0 EU per μg of the protein as determined by the LAL method

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.