- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:WB, IHC-P, ICC/IF, FC, IP
- 特异性:Human, Mouse
产品详情
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产品名称
Anti-CDK2 (1E9) Mouse antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG1
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抗体描述
CDK2 (1E9) Mouse monoclonal antibody
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抗体应用
WB, IHC-P, ICC/IF, FC, IP
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应用推荐
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
ICC: 1/200 - 1/1000
FC: 1/200 - 1/400
ELISA: 1/10000
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特异性
Human, Mouse
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制备方法
Antigen: Purified recombinant fragment of human CDK2 expressed in E. Coli.
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组分
Purified antibody in PBS with 0.05% sodium azide
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储存方法
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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背景介绍
Swiss-Prot Acc.P24941.The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.