- 抗体类型:单克隆
- 抗体来源:兔
- 抗体应用:FCM
- 特异性:Human Gastric intrinsic factor / GIF
Anti-Gastric intrinsic factor / GIF antibody
产品详情
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产品名称
Anti-Gastric intrinsic factor / GIF antibody
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抗体类型
单克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Rabbit monoclonal to Gastric intrinsic factor / GIF
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抗体应用
FCM
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应用推荐
FCM: 0.5-2 μg/Test
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特异性
Human Gastric intrinsic factor / GIF
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蛋白别名
AV073125, gastric intrinsic factor, IF, IF, IFMH, INF, INF, intrinsic factor, intrinsic factor, TCN3, IF, INF, IFMH, TCN3, AV073125
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制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human Gastric intrinsic factor / GIF (rh Gastric intrinsic factor / GIF; P27352-1; Met1-Tyr417).
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组分
0.2 μm filtered solution in PBS
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储存方法
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
背景介绍
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to gastric intrinsic factor. This new complex travels to the ileum, where special epithelial cells endocytose them. Inside the cell, B12 dissociates once again and binds to another protein, transcobalamin II. The new complex can exit the epithelial cells to enter the liver.
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参考文献
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