- 抗体类型:单克隆
- 抗体来源:兔
- 抗体应用:WB, IHC-P, ICC/IF, FC, IP
- 特异性:Human, Mouse, Rat
Anti-MBD2 Rabbit antibody
产品详情
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产品名称
Anti-MBD2 Rabbit antibody
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抗体类型
单克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
MBD2 Rabbit monoclonal antibody
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抗体应用
WB, IHC-P, ICC/IF, FC, IP
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应用推荐
1:1000
1:20-1:500
1:100
1:20
1:20
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特异性
Human, Mouse, Rat
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蛋白别名
DMTase; NY-CO-41
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制备方法
Antigen: A synthetic peptide of human MBD2
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组分
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存方法
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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背景介绍
Swiss-Prot Acc.Q9UBB5.Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
相关服务
抗体定制服务: 纽普生物（NovoPro）提供单克隆抗体及多克隆抗体定制服务