- 抗体类型:单克隆
- 抗体来源:兔
- 抗体应用:WB, FC
- 特异性:Human, Mouse, Rat
Anti-SIRP alpha Rabbit antibody
产品详情
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产品名称
Anti-SIRP alpha Rabbit antibody
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抗体类型
单克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
SIRP alpha Rabbit monoclonal antibody
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抗体应用
WB, FC
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应用推荐
1:1000
1:20
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特异性
Human, Mouse, Rat
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蛋白别名
BIT; MFR; P84; SIRP; MYD-1; SHPS1; CD172A; PTPNS1
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制备方法
Antigen: Recombinant protein of human SIRP alpha
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组分
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存方法
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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背景介绍
Swiss-Prot Acc.P78324.Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function . Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
相关服务
抗体定制服务: 纽普生物（NovoPro）提供单克隆抗体及多克隆抗体定制服务