- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IP, IHC, WB
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
ATP1A1 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
ATP1A1 Rabbit Polyclonal antibody. Positive IP detected in HEK-293 cells. Positive WB detected in mouse heart tissue, A549 cells, COLO 320 cells, HEK-293 cells, human colon tissue. Positive IHC detected in human liver cancer tissue, human ovary tumor tissue. Observed molecular weight by Western-blot: 100kd
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抗体应用
ELISA, IP, IHC, WB
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:1000
IHC: 1:20-1:200
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
ATP1A1, Na(+)/K(+) ATPase 1, Na(+)/K(+) ATPase alpha 1 subunit, Na+/K+ ATPase 1, Sodium potassium ATPase alpha 1 polypeptide, Sodium pump subunit alpha 1
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制备方法
This antibody was obtained by immunization of ATP1A1 recombinant protein (Accession Number: NM_000701). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
ATP1A1 is the catalytic component of Na+/K+-ATPase which is is a membrane bound enzyme primarily involved in generation of Na+ and K+ gradients across plasma membranes and in determination of cytoplasmic Na+ levels. ATP1A1 is a ubiquitously expressed membrane protein and often used as the marker or internal control for plasma membrane protein.
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参考文献
- Lai G, Wu J, Liu X, Zhao Y. 20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway. Molecular endocrinology (Baltimore, Md.). 26(11):1907-16. 2012.
- Xiong Q, Cao Q, Zhou Q. Arrhythmogenic cardiomyopathy in a patient with a rare loss-of-function KCNQ1 mutation. Journal of the American Heart Association. 4(1):e001526. 2015.