- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC
- 特异性:Human; other species not tested.
产品详情
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产品名称
CYP4F8 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
CYP4F8 Rabbit Polyclonal antibody. Positive IHC detected in human skin tissue, human kidney tissue.
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抗体应用
ELISA, IHC
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应用推荐
Recommended Dilution:
IHC: 1:20-1:200
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特异性
Human; other species not tested.
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蛋白别名
CPF8, CYP4F8, CYPIVF8, CytOChrome P450 4F8
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制备方法
This antibody was obtained by immunization of Peptide (Accession Number: NM_007253). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
CYP4F8, also named as CPF8, belongs to the cytochrome P450 family. Cytochromes P450 are a group of heme-thiolate monooxygenases. CYP4F8 hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. CYP4F8 shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. CYP4F8 catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid (22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid (22:5n-6). It catalyzes hydrxylation of PGI2 and carbaprostacyclin. The antibody has no cross reaction to other CYP4F member