CYP4F8 antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, IHC
  • 特异性:Human; other species not tested.

产品详情

  • 产品名称
    CYP4F8 antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    CYP4F8 Rabbit Polyclonal antibody. Positive IHC detected in human skin tissue, human kidney tissue.
  • 抗体应用
    ELISA, IHC
  • 应用推荐

    Recommended Dilution:

    IHC: 1:20-1:200

  • 特异性
    Human; other species not tested.
  • 蛋白别名
    CPF8, CYP4F8, CYPIVF8, CytOChrome P450 4F8
  • 制备方法
    This antibody was obtained by immunization of Peptide (Accession Number: NM_007253). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    CYP4F8, also named as CPF8, belongs to the cytochrome P450 family. Cytochromes P450 are a group of heme-thiolate monooxygenases. CYP4F8 hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. CYP4F8 shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. CYP4F8 catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid (22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid (22:5n-6). It catalyzes hydrxylation of PGI2 and carbaprostacyclin. The antibody has no cross reaction to other CYP4F member
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!