- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP, IF, FC, IHC
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
Cytokeratin 18 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Cytokeratin 18 Rabbit Polyclonal antibody. Positive IF detected in HeLa cells, HepG2 cells, mouse olfactory epithelium tissue. Positive IHC detected in human breast cancer tissue, human cervical cancer tissue, human colon cancer tissue, human endometrial cancer tissue, human liver cancer tissue, human lung cancer tissue, human ovary tumor tissue, human pancreas cancer tissue, human prostate cancer tissue, human stomach cancer tissue. Positive FC detected in MCF-7 cells. Positive WB detected in A431 cells, K-562 cells. Positive IP detected in A431 cells. Observed molecular weight by Western-blot: 48 kDa
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抗体应用
ELISA, WB, IP, IF, FC, IHC
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应用推荐
Recommended Dilution:
WB: 1:1000-1:10000
IP: 1:1000-1:10000
IHC: 1:50-1:500
IF: 1:20-1:200
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特异性
Human, Mouse; other species not tested.
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蛋白别名
CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18
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制备方法
This antibody was obtained by immunization of Cytokeratin 18 recombinant protein (Accession Number: NM_000224). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.
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参考文献
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