- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IF
- 特异性:Human; other species not tested.
产品详情
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产品名称
DAPK1 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
DAPK1 Rabbit Polyclonal antibody. Positive WB detected in A549 cells. Positive IF detected in A549 cells. Observed molecular weight by Western-blot: 140-160 kDa
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抗体应用
ELISA, WB, IF
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IF: 1:50-1:500
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特异性
Human; other species not tested.
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蛋白别名
DAP kinase 1, DAPK, DAPK1, DKFZp781I035
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制备方法
This antibody was obtained by immunization of DAPK1 recombinant protein (Accession Number: NM_001288730). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
DAPK1(Death-associated protein kinase 1) is a stress-activated tumor suppressor protein that plays a role in both proapoptotic or antiapoptotic signal transduction pathways. Loss of DAPK1 expression is associated with a selective advantage fortumor cells to resist apoptotic stimuli, allowing them to separate from the original tumor; from this point of view, DAPK1 could be considered a tumor metastases inhibitor gene(PMID:17319784). This protein has 3 isoforms produced by alternative splicing.