- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IP
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
-
产品名称
DOPA decarboxylase antibody
-
抗体类型
多克隆
-
抗体来源
兔
-
抗体亚型
兔IgG
-
抗体描述
DOPA decarboxylase Rabbit Polyclonal antibody. Positive IHC detected in human liver cancer tissue. Positive WB detected in mouse brain tissue, mouse kidney tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 48-50 kDa
-
抗体应用
ELISA, WB, IHC, IP
-
应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
-
特异性
Human,Mouse,Rat; other species not tested.
-
蛋白别名
AADC, DDC, DOPA decarboxylase
-
制备方法
This antibody was obtained by immunization of DOPA decarboxylase recombinant protein (Accession Number: XM_047419931). Purification method: Antigen affinity purified.
-
组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
储存方法
Store at -20℃. DO NOT ALIQUOT
-
背景介绍
Aromatic-L-amino-acid decarboxylase belongs to the pyridoxal-dependent aminotransferase superfamily.DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.DDC is the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD).Researches showed that Ddc is only one of the enzymes in the biosynthetic pathways for bioamines and catecholamines.
-
参考文献
- Ming M, Li X, Fan X. Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease. Journal of translational medicine. 7:53. 2009.
- Fox DA, Hamilton WR, Johnson JE. Gestational lead exposure selectively decreases retinal dopamine amacrine cells and dopamine content in adult mice. Toxicology and applied pharmacology. 256(3):258-67. 2011.