ERRFI1 Polyclonal Antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:WB
  • 特异性:Rat

产品详情

  • 产品名称
    ERRFI1 Polyclonal Antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    Polyclonal antibody to ERRFI1
  • 抗体应用
    WB
  • 应用推荐
    WB 1:500 - 1:2000
  • 特异性
    Rat
  • 蛋白别名
    ERRFI1, GENE-33, MIG-6, MIG6, RALT, ERBB receptor feedback inhibitor 1
  • 制备方法
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 223-462 of human ERRFI1 (NP_061821.1).
  • 组分
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 储存方法
    Store at -20℃. Avoid freeze / thaw cycles.
  • 背景介绍
    Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4. Important for normal keratinocyte proliferation and differentiation. Plays a role in modulating the response to steroid hormones in the uterus. Required for normal response to progesterone in the uterus and for fertility. Mediates epithelial estrogen responses in the uterus by regulating ESR1 levels and activation. Important for regulation of endometrium cell proliferation. Important for normal prenatal and perinatal lung development (By similarity).

抗体定制服务: 纽普生物(NovoPro)提供单克隆抗体及多克隆抗体定制服务

声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!