- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:WB
- 特异性:Human, Mouse
产品详情
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产品名称
GAB2 Polyclonal Antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Polyclonal antibody to GAB2
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抗体应用
WB
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应用推荐
WB 1:500 - 1:2000
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特异性
Human, Mouse
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蛋白别名
GAB2, GRB2-associated-binding protein 2
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制备方法
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 377-676 of human GAB2 (NP_536739.1).
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组分
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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储存方法
Store at -20℃. Avoid freeze / thaw cycles.
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背景介绍
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.