- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
GADD45A antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
GADD45A Rabbit Polyclonal antibody. Positive IP detected in K-562 cells. Positive WB detected in PC-13 cells, A549 cells, COLO 320 cells, K-562 cells, mouse lung tissue, mouse spleen tissue, rat lung tissue. Observed molecular weight by Western-blot: 18 kDa or 36 kDa
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抗体应用
ELISA, WB, IP
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
DDIT 1, DDIT1, GADD45, GADD45A
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制备方法
This antibody was obtained by immunization of GADD45A recombinant protein (Accession Number: NM_001924). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
GADD45A, also named as DDIT1 and GADD45, belongs to the GADD45 family. It binds to proliferating cell nuclear antigen. GADD45A may affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. GADD45A has Dimer (~36 kDa) and Mono (~18 kDa) forms (PMID:11498536).
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参考文献
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