Gli2 Polyclonal Antibody

0 条评论 | 添加你的评论
  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:WB, IF, FC
  • 特异性:Human

产品详情

  • 产品名称
    Gli2 Polyclonal Antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Polyclonal antibody to Gli2
  • 抗体应用
    WB, IF, FC
  • 应用推荐
    WB 1:500 - 1:1000
    IF 1:20 - 1:50
    FC 1:20 - 1:50
  • 特异性
    Human
  • 蛋白别名
    GLI2, CJS, HPE9, PHS2, THP1, THP2, zinc finger protein GLI2
  • 制备方法
    Antigen: A synthetic peptide of human Gli2
  • 组分
    PBS with 0.02% sodium azide, pH7.3.
  • 储存方法
    Store at 4℃. Avoid freeze / thaw cycles.
  • 背景介绍
    Functions as transcription regulator in the hedgehog (Hh) pathway. Functions as transcriptional activator. May also function as transcriptional repressor (By similarity). Requires STK36 for full transcriptional activator activity. Required for normal embryonic development.; Isoform 1, isoform 2, isoform 3 and isoform 4: Act as transcriptional activators in T-cell leukemia virus type 1 (HTLV-1)-infected cells in a Tax-dependent manner. Bind to the DNA sequence 5'-GAACCACCCA-3' which is part of the Tax-responsive element (TRE-2S) regulatory element that augments the Tax-dependent enhancer of HTLV-1. Are involved in the smoothened (SHH) signaling pathway.; Isoform 5: Acts as a transcriptional repressor.
声明：本公司出售产品只能用于科研目的，不得用于诊断或者治疗！