重组人CLEC16A蛋白

产品详情

  • 产品名称
    重组人CLEC16A蛋白
  • 蛋白种属
    人
  • 表达宿主
    大肠杆菌
  • Unitprot ID
    Q2KHT3
  • 蛋白序列
    1-350
  • 克隆构建
    A DNA sequence encoding the human CLEC16A (NP_001397834.1) 1-350 aa was fused with the polyhistidine tag
  • 蛋白活性
    Not tested.
  • 蛋白别名
    KIAA0350
  • 蛋白全名
    Protein CLEC16A
  • 蛋白描述
    Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health. {PubMed:24949970}.
  • 发货形式
    Protein lyophilized in sterile PBS (58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, 300 mM Imidazole, pH 8.0). Trehalose (5-8%) and mannitol (5-8%) protectants were added before lyophilization.
  • 内毒素
    Please contact the lab for more information.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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