重组人FKBP2蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human FKBP2/FKBP13 Ala22-Leu142 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

FKBP13

FK506 binding protein 2(FKBP2)

Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds.

Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mm NaCl,pH7.5.

<1.0 EU per μg protein as determined by the LAL method.

Store at <-20°C, minimize freeze-thaw cycles.