重组大鼠EFNB3蛋白

产品详情

  • 产品名称
    重组大鼠EFNB3蛋白
  • 蛋白种属
    大鼠
  • 表达宿主
    人胚胎肾细胞(HEK293)
  • Unitprot ID
  • 克隆构建
    A DNA sequence encoding the rat EFNB3 (NP_001094450) (Met1-Ser224) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
  • 蛋白纯度
    (79.6+17) % as determined by SDS-PAGE
  • 蛋白活性
    Measured by its binding ability in a functional ELISA.
    Immobilized mouse EphB3-His (Cat:500494) at 10 μg/ml (100 μl/well) can bind rat EFNB3-Fc, The EC50 of rat EFNB3-Fc is 14.1-33.2 ng/ml.
  • 分子量
    The recombinant rat EFNB3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 438 amino acids and has a predicted molecular mass of 48.7 kDa. The apparent molecular mass of the protein is approximately 55 and 34 kDa in SDS-PAGE under reducing conditions.
  • 蛋白别名
    EPLG8; EPHRIN B3 / EFNB3; RP23-56I20.5; ELF-3; EPL8; LERK-8; EPH-RELATED RECEPTOR TRANSMEMBRANE LIGAND ELK-L3; ELK-L3; EFL-6; LERK8; EPH-RELATED RECEPTOR TYROSINE KINASE LIGAND 8; EFL6; EPHRIN-B3; NLERK-2
  • 蛋白全名
    Ephrin B3 (Predicted)
  • 蛋白描述
    Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin B3 is important in brain development as well as in its maintenance. It is especially important for forebrain function since its expression levels were particularly high in several forebrain subregions compared to other brain subregions. Ephrin B3 binds to, and induce the collapse of, commissural axons/growth cones in vitro. It may play a role in constraining the orientation of longitudinally projecting axons.
  • 发货形式
    Lyophilized from sterile PBS, pH 7.4
    1. 5 % trehalose and mannitol are added as protectants before lyophilization.
    2. Please contact us for any concerns or special requirements.
  • 内毒素
    < 1.0 EU per μg of the protein as determined by the LAL method
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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