Introducing the recombinant Apolipoprotein A-I (Apo-AI) fragment (residues 94-267), a highly stable and soluble protein unit ideal for structural and biochemical studies. This fragment, derived from human Apo-AI, retains key functional relevance for investigating cholesterol transport mechanisms and related metabolic pathways.

Apolipoprotein A-I (Apo-AI) is a secreted protein crucial for the reverse transport of cholesterol, facilitating efflux from tissues and acting as a cofactor for lecithin cholesterol acyltransferase (LCAT) to promote cholesterol excretion in the liver. It also plays a role in sperm motility activation as part of the SPAP complex. The full-length protein's localization to the secretory pathway underscores its systemic role in lipid metabolism and cardiovascular health.