The original source of Dermorphin is Sauvage's leaf frog (Phyllomedusa sauvagei), Brazilian orange-legged leaf frog (Phyllomedusa hypochondrialis), Jandaia leaf frog (Phasmahyla jandaia). Potent and selective natural opioid that binds as an agonist to μ-opioid receptors. 30–40 times more potent than morphine. Antinociceptive effect. CAS Number: 77614-16-5
Montecucchi PC, De castiglione R, Piani S, Gozzini L, Erspamer V. Amino acid composition and sequence of dermorphin, a novel opiate-like peptide from the skin of Phyllomedusa sauvagei. Int J Pept Protein Res. 1981;17(3):275-83.