重组人QPCT蛋白

人

杆状病毒 - 昆虫细胞

Ala 33 - Leu 361

A DNA sequence encoding the human QPCT (Q16769-1) (Ala33-Leu361) was fused with a polyhistide tag at the N-terminus.

> 95 % as determined by SDS-PAGE

The recombinant human QPCT consists of 345 amino acids and has a calculated molecular mass of 39.7 kDa. The recombinant protein migrates as an approximately 38 kDa band in SDS-PAGE under reducing conditions.

GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE (GLUTAMINYL CYCLASE); QPCT; QC; EC; GLUTAMINYL CYCLASE; GLUTAMYL CYCLASE; 5730422A13RIK; GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE; GLUTAMINYL-TRNA CYCLOTRANSFERASE; GCT; SQC

Glutaminyl-peptide cyclotransferase

Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

< 1.0 EU per μg of the protein as determined by the LAL method

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.