重组人CDC73蛋白
- 蛋白种属:人
- 表达宿主:大肠杆菌
- Unitprot ID:Q6P1J9
产品详情
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产品名称
重组人CDC73蛋白
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蛋白种属
人
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表达宿主
大肠杆菌
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Unitprot ID
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克隆构建
A DNA sequence encoding the Human CDC73/C1orf28/HRPT2 Met1-Glu260 is expressed with a 6His tag at the N-terminus.
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蛋白纯度
>95% as determined by SDS-PAGE.
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蛋白别名
C1orf28; HRPT2
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蛋白全名
cell division cycle 73(CDC73)
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蛋白描述
Parafibromin is expressed in the adrenal and parathyroid glands, kidney, and heart. As a tumor supressor, Parafibromin may be involved in transcriptional and post-transcriptional control pathways, also through the regulation of cyclin D1/PRAD1 expression, involved the cell cycle progression. Parafibromin is a component of the the PAF protein complex and interacts with a Set1-like complex that has histone methyltransferase activity and methylates histone H3. Defects in Parafibromin can cause hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
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发货形式
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
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内毒素
<1.0 EU per μg protein as determined by the LAL method.
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保存条件
Lyophilized protein should be stored at <-20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
重组蛋白定制服务:
纽普生物(NovoPro)提供大肠杆菌、哺乳细胞、昆虫细胞和酵母细胞重组蛋白定制服务
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!