重组人CST7蛋白

人

人胚胎肾细胞（HEK293）

Met 1 - His 145

The mature form of the human Cystatin F (NP_003641.3) (Met 1-His 145) with five amino acids (DDDDK) at the C-terminus was expressed and purified.

> 95 % as determined by SDS-PAGE

The recombinant human Cystatin F consists of 132 amino acids and predicts a molecular mass of 15.2 kDa. As a result of glycosylation, the apparent molecular mass of rhCystatin F is approximately 25 kDa in SDS-PAGE.

CST7; MGC151424; CMAP; CYSTATIN F; RP23-156P22.1; MGC151426

Cystatin-F

The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.

Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

< 1.0 EU per μg of the protein as determined by the LAL method

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.