重组人GNAS蛋白
产品详情
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产品名称
重组人GNAS蛋白
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蛋白种属
人
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表达宿主
大肠杆菌
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Unitprot ID
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蛋白序列
874-1038
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克隆构建
A DNA sequence encoding the human GNAS (XP_016883301.1) 874-1038 aa was fused with the N-terminal GST tag
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蛋白活性
Not tested.
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蛋白别名
GNAS1; GSP
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蛋白全名
Guanine nucleotide-binding protein G(s subunit alpha isoforms short
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蛋白描述
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135). Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161). {PubMed:12391161, PubMed:17110384, PubMed:21488135, PubMed:26206488, PubMed:8702665}.
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发货形式
PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4).
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内毒素
Please contact the lab for more information.
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保存条件
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
重组蛋白定制服务:
纽普生物(NovoPro)提供大肠杆菌、哺乳细胞、昆虫细胞和酵母细胞重组蛋白定制服务
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!