重组人GNAS蛋白

产品详情

  • 产品名称
    重组人GNAS蛋白
  • 蛋白种属
    人
  • 表达宿主
    大肠杆菌
  • Unitprot ID
    A0A7I2V5R6
  • 蛋白序列
    874-1038
  • 克隆构建
    A DNA sequence encoding the human GNAS (XP_016883301.1) 874-1038 aa was fused with the N-terminal GST tag
  • 蛋白活性
    Not tested.
  • 蛋白别名
    GNAS1; GSP
  • 蛋白全名
    Guanine nucleotide-binding protein G(s subunit alpha isoforms short
  • 蛋白描述
    Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135). Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161). {PubMed:12391161, PubMed:17110384, PubMed:21488135, PubMed:26206488, PubMed:8702665}.
  • 发货形式
    PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4).
  • 内毒素
    Please contact the lab for more information.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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