重组人SEMA4B蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human SEMA4B/KIAA1745/SEMAC Leu39-Glu712 is expressed with a Fc, 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

KIAA1745; SEMAC; UNQ749; PRO1480

semaphorin 4B(SEMA4B)

Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

<1.0 EU per μg protein as determined by the LAL method.

Lyophilized protein should be stored at <-20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.